Lucio la reina del flow7/25/2023 ![]() ![]() Descriptive analysis of individuals’ characteristics was carried out using frequency tables with percentages for categorical variables and median and quartiles for continuous variables. The main outcome was all‐cause in‐hospital mortality. The COVID‐19 SEIMC score (predictive of 30‐day mortality), based on age, sex, dyspnoea, oxygen saturation, neutrophil‐to‐lymphocyte ratio and estimated glomerular filtration rate, was calculated retrospectively at admission in all patients. COVID‐19‐related clinical data were collected from the electronic medical records using an electronic case report form.Įach hospitalized PWH with COVID‐19 was matched with five hospitalized non‐PWH with COVID‐19 of the same age and sex randomly selected from a multicentre cohort of 4035 patients hospitalized with PCR‐confirmed COVID‐19 in Spain. The data source for demographics, HIV‐related characteristics and comorbidities in this study was the CoRIS database. PWH with confirmed COVID‐19 in CoRIS were identified by reviewing clinical records and laboratory registries. Internal quality controls are done annually. The CoRIS database collects demographic and clinical data, HIV transmission category, ART history, previous opportunistic diseases, specific non‐AIDS diseases, and serological and immunovirological data. CoRIS is a prospective cohort of PWH aged > 13 years, naïve to antiretroviral therapy (ART) at study entry, seen for the first time from 1 January 2004, in 46 participating centres from 13 of 17 regions in Spain. We performed a retrospective study of individuals with reverse transcription polymerase chain reaction (PCR)‐confirmed COVID‐19 among PWH in active follow‐up within the Spanish HIV Research Network Cohort (CoRIS) up to 30 June 2020. We assessed the frequency of COVID‐19 within a large prospective cohort of PWH in Spain during the first wave of the pandemic and compared the characteristics and clinical outcomes of hospitalized PWH with COVID‐19 with an age/sex‐matched control group of non‐PWH. In four of these studies, worse outcomes in PWH vs. Many studies have analysed the characteristics and outcomes of COVID‐19 in PWH, but to the best of our knowledge, only in eight of these has some comparison been made between PWH and people without HIV (non‐PWH). Notwithstanding this, whether HIV increases the risk of acquiring SARS‐CoV‐2 or the severity or mortality of COVID‐19 has stirred substantial research. This is likely because of the much lower prevalence of HIV among the general population than that of other prevailing diseases and because the number of older individuals is much lower among people with HIV (PWH) than among the HIV‐uninfected population (non‐PWH). ![]() Since the beginning of the COVID‐19 pandemic, HIV has been uncommonly listed as an underlying condition in case series of hospitalized patients with COVID‐19.
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